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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD7
All Species:
6.67
Human Site:
S441
Identified Species:
14.67
UniProt:
Q6ZUT3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZUT3
NP_919253.1
714
81614
S441
R
D
I
F
S
E
R
S
S
L
S
S
F
Q
T
Chimpanzee
Pan troglodytes
XP_001142428
1045
118548
H479
G
S
L
T
G
S
P
H
L
S
E
L
S
V
N
Rhesus Macaque
Macaca mulatta
XP_001095803
714
81414
S441
R
D
F
F
S
E
R
S
P
L
S
S
F
Q
T
Dog
Lupus familis
XP_549262
787
88688
S518
G
E
R
S
P
L
S
S
F
Q
P
S
S
K
F
Cat
Felis silvestris
Mouse
Mus musculus
A2AD83
703
80312
S441
E
E
R
S
P
L
S
S
F
Q
T
T
S
K
F
Rat
Rattus norvegicus
Q9WTP0
879
98224
L538
D
W
E
R
E
R
R
L
P
S
S
P
A
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506249
1047
119790
P479
T
G
S
L
T
G
S
P
H
L
S
E
L
S
I
Chicken
Gallus gallus
XP_426268
693
77887
E429
L
E
L
E
R
A
W
E
P
T
D
S
F
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Q358
T
Y
P
K
R
S
T
Q
P
A
G
R
N
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
G561
V
A
K
A
A
A
R
G
L
P
P
T
N
Q
Q
Sea Urchin
Strong. purpuratus
XP_792466
1673
187206
P535
S
F
N
A
R
M
E
P
E
P
I
M
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
95.3
79
N.A.
85.1
23.8
N.A.
30.7
65.5
N.A.
24.2
N.A.
N.A.
N.A.
22.8
20.8
Protein Similarity:
100
44.7
96.5
82.8
N.A.
90
37.6
N.A.
44.8
75.9
N.A.
43.5
N.A.
N.A.
N.A.
38.5
30.2
P-Site Identity:
100
0
86.6
13.3
N.A.
6.6
13.3
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
6.6
86.6
26.6
N.A.
33.3
13.3
N.A.
20
33.3
N.A.
0
N.A.
N.A.
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
10
19
0
0
0
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
28
10
10
10
19
10
10
10
0
10
10
0
0
0
% E
% Phe:
0
10
10
19
0
0
0
0
19
0
0
0
28
0
19
% F
% Gly:
19
10
0
0
10
10
0
10
0
0
10
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
10
10
0
0
0
0
0
0
0
0
0
19
0
% K
% Leu:
10
0
19
10
0
19
0
10
19
28
0
10
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
19
10
10
% N
% Pro:
0
0
10
0
19
0
10
19
37
19
19
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
19
0
0
0
28
10
% Q
% Arg:
19
0
19
10
28
10
37
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
10
19
19
19
28
37
10
19
37
37
37
37
10
% S
% Thr:
19
0
0
10
10
0
10
0
0
10
10
19
0
0
19
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _